Fig. 6: C. auris can scavenge CO2 released by bacterial skin colonizers.
From: Candida auris skin tropism and antifungal resistance are mediated by carbonic anhydrase Nce103
a, A schematic illustration depicts how urease-positive bacteria supply CO2 to the CSP of C. auris. b, Hospital-acquired bacteria can promote growth of C. auris by releasing CO2 through the urease pathway. Experiments were performed on 12-well plates, where bacterial cell suspensions were spotted in the two middle columns and fungal cell suspensions in both outer columns. Each fungal strain was tested at three levels of 10-fold dilutions. The plates were covered, sealed in plastic bags and incubated at 37 °C for 24 h (Extended Data Fig. 7d). Representative data from at least three independent experiments.
