Extended Data Fig. 1: Sample accumulation curve, and comparison of microbiome enzymatic potential between gut microbiota and probiotics.
From: Gut microbiome-mediated transformation of dietary phytonutrients is associated with health outcomes
a, Sample accumulation curve of microbial enzymes, phytonutrient-associated microbial enzymes and microbial species for different continents (Africa, Europe, America, Oceania and Asia). The x-axis represents the number of samples. b, Ratios of ECs detected by HUMAnN3 to the total ECs present in the corresponding species from the ChocoPhlAn database under different species prevalence thresholds (left) and different species abundance thresholds (right). The x-axis represents the applied threshold values; the y-axis represents the calculated ratio. The two horizontal dashed lines represent ratios of 0.90 and 0.95, respectively. c, Pie chart showing phytonutrients that can be modified either exclusively by gut bacteria (designated ‘gut-restricted’) or by gut bacteria and probiotics (designated ‘shared’). d, Phytonutrient accumulation curve with combined biotransformation potential covering 106 ‘gut-restricted’ non-primary metabolism related phytonutrients. The horizontal line represents 80% of the total phytonutrients and the vertical line marks the species rank at which the cumulative phytonutrient number just exceeds 80%. Boxplots show the median (centrelines), first and third quartiles (box limits) and 1.5x interquartile range bounds (whiskers).
