Extended Data Fig. 4: Loss of heterozygosity (LOH) events during parasex.
From: Parasex generates highly recombinant progeny in Candida albicans with increased virulence
A. A schematic showing LOH events in parasexual progeny by scanning for homozygosis of heterozygous and unique alleles from one parental background. All informative markers for detecting LOH must have at least 3 separate alleles among the parental strains. B. The number of LOH events in parasexual progeny from SC5314x529L and SC5314xP60002 matings were quantified and plotted as violin plots. Significance was determined by a Kruskal-Wallis test. *** denotes p < 0.001. N = 47 and 37 for the SCx529L and SCxP60002 groups, respectively. The position of LOH events were determined and plotted as the frequency of markers in 100 kb bins that detect LOH across the C. albicans genome for the SC5314x529L ddRAD-Seq (C), SC5314xP60002 ddRAD-Seq (D), and SC5314x529L WGS (E) parasexual progeny. Panel a created with BioRender.com.
