Extended Data Fig. 3: Tissue biopsy viral loads are comparable between experimental groups during ART.
From: Initial sites of SIV rebound after antiretroviral treatment cessation in rhesus macaques
a, b, The amount of vDNA (a) and vRNA (b) from on-ART biopsy samples from peripheral LN (pLN), mesenteric LN (mLN), spleen, bone marrow, duodenum, rectum, and liver at 12 dpi, 21 wpi, and 66 wpi was not significantly different between macaques based on the assigned experimental groups (on-ART necropsy or with necropsy after 5 or 7 days off ART). Kruskal-Wallis test was used for each individual time point assessed. Open symbols plotted below the dotted line represent samples below the limit of detection, which varied depending on specimen input. [horizontal black lines indicate median value in all panels with the n values reflecting the number of samples with DNA or RNA levels above the limit of detection].
