Extended Data Fig. 5: Engraftment of the RCom in SPF mice.
a, SPF mice were supplemented with the RCom (n = 5) or its subsets (PBS, n = 4; 5-mix, n = 4; 10mix-I, n = 5) daily by oral gavage for 7 days. The abundance of each of the 15 species in caecal samples was determined by qPCR and normalized to 16S rRNA level. Each species was denoted by two-letter abbreviation, and the color represents the phyla of the species (Bacteroidetes, blue; Firmicutes, green). b, Heat map showing the changed metabolites in the caecal content of mice supplemented with the indicated bacterial mixtures. Elevated metabolites in RCom- versus subset-supplemented mice are highlighted in red. Exact P values are provided in Source Data. Data in a are mean and s.e.m. Two-tailed unpaired t-test. NS, not significant.
