Extended Data Fig. 9: A model for YokF anti-NPex activity.
From: A family of endonucleases blocks nanotube-mediated plasmid exchange
Schematic illustrating the mechanism by which YokF inhibits NPex. Following membrane localization, YokF undergoes a proteolytic cleavage, leading to TNM secretion and TNase activation. Activated YokF interacts with the CORE component FlhA, degrading plasmid DNA in the nanotube vicinity, thereby impeding NPex. An enlarged view shows YokF action site. Figure created in BioRender; Ben-Yehuda, S. https://BioRender.com/gum4ra9 (2026).
