Extended Data Fig. 1: Schematic illustrating the covalent incorporation of aqueous n:3 FTCAs into the bacterial lipid bilayer and the formation of fluoromembranes. | Nature Microbiology

Extended Data Fig. 1: Schematic illustrating the covalent incorporation of aqueous n:3 FTCAs into the bacterial lipid bilayer and the formation of fluoromembranes.

From: Bacteria covalently incorporate polyfluoroalkyl carboxylates into membrane lipids

Extended Data Fig. 1: Schematic illustrating the covalent incorporation of aqueous n:3 FTCAs into the bacterial lipid bilayer and the formation of fluoromembranes.

The fluoromembrane structure displays a fluorinated glycerophospholipid with an n:3 FTCA (n = 5, 7, 8, 9) acyl tail covalently attached to the glycerol backbone at the sn1 position. Free n:3 FTCA and n:3 FTCA that partitions into membranes due to hydrophobic interactions are shown in blue color, while covalently incorporated n:3 FTCA is depicted in red. Note that the covalent incorporation and the non-covalent partitioning of n:3 FTCA into lipid membrane are mechanistically distinct and likely occur simultaneously.

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