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Metagenomic surveillance of zoonotic yellow fever and spillover dynamics at a forest–urban interface

We studied the interactions between hosts, vectors and the environment during a zoonotic yellow fever outbreak at the urban–forest edges of metropolitan São Paulo. Our analyses indicate that a single introduction drove most infections; its high transmission potential (R0 ≈ 8.2) led to local extinction of the resident howler monkey population within around 46 days.

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Fig. 1: Timing, spread and epidemiological impact of YFV introductions in PEAL State Park.

References

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This is a summary of: Telles-de-Deus, J. et al. Evolution and spillover dynamics of yellow fever at the forest–urban interface in Brazil. Nat. Microbiol. https://doi.org/10.1038/s41564-026-02302-w (2026).

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Metagenomic surveillance of zoonotic yellow fever and spillover dynamics at a forest–urban interface. Nat Microbiol (2026). https://doi.org/10.1038/s41564-026-02305-7

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