Extended Data Fig. 3: Chemotaxis behaviour of CM/NM/Mito.
From: Oral mitochondrial transplantation using nanomotors to treat ischaemic heart disease
a. Schematic illustration of the Y channel. b-e. Fluorescence images (120 min) and corresponding quantitative analysis of the normalized fluorescence intensity in reservoir ii and iii at different time after addition of CM/NM/Mito (b and c) and unmodified mitochondria (d and e) (scale bar: 500 μm; n = 3 biologically independent samples). f. Schematic illustration of the Ψ microfluidic device. g. Fluorescence images and corresponding fluorescence intensity distribution of CM/NM/Mito and unmodified mitochondria in the microfluidic device applying gradient concentrations of damaged H9c2 cell lysate and normal H9c2 cell lysate (scale bar: 500 μm). h. Fluorescence images and fluorescence intensity distribution of CM/NM/Mito and unmodified mitochondria in the microfluidic device applying gradient concentrations of normal H9c2 cell lysate (scale bar: 500 μm). Data are presented as means ± SD. Statistical significance was calculated via two-tailed unpaired Student’s t test in c, e.
