Extended Data Fig. 6: Mechanism study of GO-APP3/28-stimulated T cell activation at the protein expression level. (Related to Fig. 4). | Nature Nanotechnology

Extended Data Fig. 6: Mechanism study of GO-APP3/28-stimulated T cell activation at the protein expression level. (Related to Fig. 4).

From: Biomimetic cell stimulation with a graphene oxide antigen-presenting platform for developing T cell-based therapies

Extended Data Fig. 6

a-b, Flow cytometry analysis of GO-APP3/28 T cells and Beads3/28 T cells. a, Flow plots showing the indicated intracellular protein expression. b, Mean fluorescence intensity (MFI) measurement from flow cytometry showing the TCR and IL-2 signaling pathway molecules in GO-APP3/28 T cells and Beads3/28 T cells at the protein level (number of samples n = 3). Data are presented as mean values ± SEM. (Related to Fig. 4o) Pairwise comparisons were made using a 2-tailed Student’s t test. p values less than 0.05 were considered significant. ‘ns’ denotes not significant; * denotes p value < 0.05; ** denotes p value < 0.01; *** denotes p value < 0.001; **** denotes p value < 0.0001.

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