Extended Data Fig. 4: Cancer vaccination effect of TITUR-4T1 LNPs in 4T1 recurrence tumour model.
From: A modular mRNA platform for programmable induction of tumour-specific immunogenic cell death
a, Tumour luminescence monitoring for primary and rechallenge 4T1-Fluc orthotopic tumours. Data is shown as IVIS images for each mouse, with n=5 mice per treatment group. Colour bar corresponds to luminescence intensity corresponding to this scale. b, Violin plots representing the percentage of each immune cell population in the tumour, spleen, and lymph nodes with n=5 mice per treatment group. c. Cytokine levels for each mouse per treatment group are shown in the heatmap, with n=5 mice per group. Statistical significance was determined by one-way ANOVA with multiple comparisons.
