Extended Data Fig. 11: Different GalNAc operon structure and transcriptome response in miQTL-sensitive versus -insensitive GalNAc utilizing bacteria.
From: ABO genotype alters the gut microbiota by regulating GalNAc levels in pigs
Maps of GalNAc “operons” in one of the two OTU476-like strains (NB: The organization of the GalNAc gene cluster was identical in both 4-15-1 and 4-8-110 strains), and six MAGs assigned respectively to an Erysipelotrichaceae, E. coli (an Enterobacteriaceae), a Collinsella (a Coriobacteriaceae), a Fusobacteriaceae, a Firmicutes and a Clostridium. Identified Open Reading Frames (ORFs) are represented as coloured boxes. Genes implicated in GalNAc import and catabolism are in red if they are part of the cluster and in green if located elsewhere in the genome. Genes with a known function unrelated to GalNAc are in blue. ORFs with uncharacterized gene product in gray. Gene acronyms are given next to the corresponding boxes. ORFs transcribed from the top (respectively bottom) strand are above (below) the dotted line. The respective transcriptional directions are marked by the arrows. The source of information used to confirm the map order is given (finished genome, multiple MAGs, single contig).
