Extended Data Fig. 3: Longitudinal measurements of CD4+ T cell counts and phenotypic analyses of CD8+ T cells.
From: Combination anti-HIV antibodies provide sustained virological suppression
a. Levels of CD4+ T cell counts of the bNAb (n = 7) and placebo (n = 7) arms of Group 1 and Group 2 (n = 5) study participants are shown. b. Frequencies of the activation/exhaustion markers TIGIT, PD-1, CD38 and HLA-DR (left) and T cell subsets (TN, naive; TCM, central memory; TTM, transitional memory; TEM, effector memory; TTD, terminally differentiated) on CD8+ T cells of the bNAb (n = 5) and placebo (n = 7) arms of Group 1 and Group 2 (n = 5) study participants are shown. The grey lines indicate median values. P values were determined using the two-sided Wilcoxon matched-pairs signed rank test and were adjusted for multiple testing. ns, not significant.
