Extended Data Fig. 8: Principal component analysis and Western blotting.
From: Dual regulation of mitochondrial fusion by Parkin–PINK1 and OMA1
(a) Principal component analysis of bulk RNA-seq data. (b) Postnuclear supernatants and mitochondrial fractions from WT and Parkin−/−Oma1−/− pons/medulla were analyzed by Western blotting using antibodies against Tim23 and α-tubulin. (c) qPCR analysis of the mitochondrial fraction from WT and Parkin−/−Oma1−/− pons/medulla (mean ± SD, n = 3). Significance was determined using two-tailed Student’s t-test.
