Extended Data Table 1 SPR-derived affinity of SHOC2-RAS binary interactions

From: Targeting the SHOC2–RAS interaction in RAS-mutant cancers

  1. Binary affinity between various immobilized RAS constructs and SHOC2 (aa80-582). Means ± SD of n = 3 (GMPPNP) and n  =  2 (GDP, GTP) measurements are shown. *Weak binding, KD ill defined, at least one value with low binding efficiency (15–50%).