Extended Data Fig. 3: Resolution and electron density map of NvACE2:MRCoV RBD complex and structural comparison of RBDs of different MERS-CoV-related CoVs. | Nature

Extended Data Fig. 3: Resolution and electron density map of NvACE2:MRCoV RBD complex and structural comparison of RBDs of different MERS-CoV-related CoVs.

From: A MERS-CoV-like mink coronavirus uses ACE2 as an entry receptor

Extended Data Fig. 3: Resolution and electron density map of NvACE2:MRCoV RBD complex and structural comparison of RBDs of different MERS-CoV-related CoVs.

a, Fourier shell correlation (FSC) of the half cryo-EM maps, using gold standard protocol (FSC = 0.143). b, Electron density of key interacting residues in the structure of NvACE2 (green mesh) and MRCoV RBD (yellow mesh) complex. c, Comparison of the structure of MRCoV RBD with RBDs of NeoCoV, PDF-2180-CoV, BatCoV-HKU4, BatCoV-HKU5 and MERS-CoV. Figure was created with PyMOL from PDB-files 8ZWE (MRCoV), 7WPO (NeoCoV), 7WPZ (PDF-2180-CoV), 4QZV (BatCoV-HKU4), 5XGR (BatCoV-HKU5), and 4KR0 (MERS-CoV).

Back to article page