Extended Data Fig. 4: QC Framework and Cell Type Annotation for the Pan-Cancer scRNA-seq Dataset.
From: Concurrent loss of the Y chromosome in cancer and T cells impacts outcome
a. Schematic depicting tumor sources of the human scRNA-seq pan-cancer datasets developed and analyzed in this study. b. Quality control metrics for the pan-cancer scRNA-seq datasets with vertical lines indicating selection criteria: 400 <Gene counts <5500 (top) and 500 <Total counts <30,000 (center and bottom) for further analysis. c. Cells from the pan-cancer scRNA-seq data colored by original dataset (top left), organ (top right), sex information (bottom left) and cancer type (bottom center) and major cell type (bottom right). d. Expression levels of marker genes across the major cell types identified in the pan-cancer scRNA-seq datasets. Dot size indicates the proportion of expressing cells and color indicates mean expression levels.
