Extended Data Table 1 In vitro efficacy characterisation of JNJ-6640

From: Targeting de novo purine biosynthesis for tuberculosis treatment

  1. MIC90 values in selected media conditions, species, strains and assays. n = ≥2 independent experiments consisting of ≥2 technical replicates. Data shown are mean ± SD. Erdman and clinical isolate MIC90 performed once. INH: Isoniazid; RMP: Rifampicin; EMB: Ethambutol; AMK: Amikacin; TAC: Thiacetazone; SM: Streptomycin; OFL: Ofloxacin. S: drug sensitive; R: drug resistant. MIC: Minimum inhibitory concentration. Fold change compared to Mtb H37Rv strain.
Back to article page