Extended Data Fig. 3: Residual 0xWGD cells in WGD-high patients.
From: Ongoing genome doubling shapes evolvability and immunity in ovarian cancer
a-f. Total copy-number profiles for patient OV-045 pseudobulk and all non-divergent 0xWGD cells. Each point is a 500 kb bin colored by its assigned copy-number state, the y-axis shows scaled GC-corrected read depth, and the x-axis shows genomic position. The top track of each panel shows the pseudobulk profile for all filter-passing cells (note that average total copy number, i.e., ploidy, is close to 3N-4N indicating WGD), and each lower track shows a single cell. b. Total copy-number profiles for OV-051 pseudobulk and all non-divergent 0xWGD cells as defined in a. c. Total copy-number profiles for OV-075 pseudobulk and all non-divergent 0xWGD cells as defined in a. d. Total copy-number profiles for OV-087 pseudobulk and all non-divergent 0xWGD cells as defined in a. e. Total copy-number profiles for OV-107 pseudobulk and all non-divergent 0xWGD cells as defined in a. f. Total copy-number profiles for OV-110 pseudobulk and all non-divergent 0xWGD cells as defined in a.
