Extended Data Fig. 8: Co-expression profiles for SOX9 against PTN and MK pathways and SOX9’s downstream targets at E45, E53.

Anatomical location of each Visium spatial section is depicted by a red line on the reconstructed model. Top row for E45 and E53 are gene expression profiles for each target gene, and the bottom row depicts the co-expression plots. The heatmap beneath each co-expression plot highlights spatial spots, with SOX9 expression shown in dark red, expression of the compared gene in yellow, and co-expression of both genes in orange. Abbreviations: Fe, femur; il, ilium.