Fig. 1: Survey of developing inhibitory neurons reveals conservation of initial classes across placental mammals.
From: Conservation and alteration of mammalian striatal interneurons
a, Phylogeny of placental mammals surveyed. Ma, million years ago. b, Stages surveyed compared to human development. PCD, post-conception day. c, Uniform manifold approximation and projection (UMAP) coloured by integrated inhibitory neuron initial classes and individual species (n = 75,000 inhibitory neurons), and key for d,e. d, Heat map of selected markers of inhibitory neuron initial classes plotted by individual species, scaled and normalized. Grey boxes indicate that no cells from that species contribute to the integrated cluster, e, Similarity matrix of Pearson correlations based on principal component analysis (PCA) of initial classes from integrated clusters across species.
