Extended Data Table 8 Positive Predictive Value and Negative Predictive Value sensitivity analysis by age group

From: Prevalence of Alzheimer’s disease pathology in the community

  1. yr = year; PPV = Positive Predictive Value; NPV = Negative Predictive Value; Se = Sensitivity; Sp = Specificity. Unpenalized analysis: Se: 0.850–0.982; Sp: 0.745–0.986; medians with 2.5–97.5% quantiles. Optimism-corrected: Se/Sp shrunk 10% toward 0.5 (Se* = 0.5 + 0.9·(Se−0.5); Sp* analogous).
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