Extended Data Fig. 10: Vancomycin pharmacokinetics and markers of infection.
From: Physiology and immunology of a pig-to-human decedent kidney xenotransplant
(A) Vancomycin trough levels were measured to assess the need to modify dosing based on improving creatinine clearance. The median vancomycin trough level was therapeutic at 12.75 μg/mL. (B) White blood cell (WBC) and platelet counts are displayed over the course of the study. The median WBC and platelet counts following reperfusion were 6.8 × 10³/μL (IQR 5–8.2 × 10³/μL) and 124 × 10³/μL (IQR 94–174.9 × 10³/μL), respectively, throughout the duration of xenograft perfusion up to day 61.
