Extended Data Fig. 1: Correlation of serum albumin level with antifungal activity, albumin purification, and evaluation of other serum proteins. | Nature

Extended Data Fig. 1: Correlation of serum albumin level with antifungal activity, albumin purification, and evaluation of other serum proteins.

From: Albumin orchestrates a natural host defence mechanism against mucormycosis

Extended Data Fig. 1: Correlation of serum albumin level with antifungal activity, albumin purification, and evaluation of other serum proteins.

a, Correlation between serum albumin levels and R. delemar growth in human sera obtained from patients with cirrhotic disease (n = 18, left) or haematologic malignancies (n = 20, right). Simple linear regression test was used to determine deviation from zero. b, Outline of human serum isolation using blue Sepharose columns. c, Immunoblot analysis of albumin and transferrin in human serum and eluted fragments following isolation. Representative image from 3 independent experiments. d, Representative images of R. delemar spores cultured for 8 h in medium alone or medium supplemented with increasing concentrations of human IgG. Representative images from 3 independent experiments performed in triplicate. Scale bar, 20 µm.

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