Extended Data Fig. 2: Selective fungistatic activity of albumin against Mucorales.
From: Albumin orchestrates a natural host defence mechanism against mucormycosis
a, Representative images of R. delemar dormant spores (upper panel) or germinating spores (lower panel) cultured for 10 h in medium alone, medium + BSA, or medium + HSA. Scale bar, 50 µm. b, Assessment of R. delemar germination in medium alone, medium supplemented with human serum albumin (medium + albumin), or medium alone following initial incubation in albumin-containing medium (fresh medium) (n = 5 independent experiments). Data are mean ± s.d. ns = 0.437; ****p < 0.0001, one-way ANOVA with Tukey’s multiple comparisons post hoc test. c, Representative fluorescence images of different human fungal pathogens labelled with CFW-and cultured for 6 h in medium ± 4.5 g dl−1 albumin. Scale bar, 20 µm.
