Extended Data Fig. 1: Comparison of origin mapping by OK–seq, Ori–seq-HU and scEdU–seq.
From: CFAP20 salvages arrested RNAPII from the path of co-directional replisomes
a, Comparison of analysis of published OK–seq data5 with Ori–seq in HU-treated RPE1 cells20 in a 5 Mbp region of chromosome 2. b, Mean replication timing based on scEdU–seq21 of origins mapped by OK–seq5 in unperturbed RPE1 cells. n = 402 cells. The box plot is defined by the median ± interquartile range (IQR) and whiskers are 1.5 x IQR. c, Comparison of Ori–seq from20, OK–seq from5, and scEdU–seq in unperturbed RPE1 cells from21. Histone marks (H3K36me3 and H3K9me3) and nascent transcription (scEU–seq) are shown for comparison.
