Extended Data Fig. 10: Distribution of temporally shifting cells across mice. | Nature

Extended Data Fig. 10: Distribution of temporally shifting cells across mice.

From: Predictive coding of reward in the hippocampus

Extended Data Fig. 10

a, The top row shows the total number of tracked cells for each cell type; the second row provides the breakdown by mouse (mouse 2 had poor cell tracking and was excluded from this analysis). Each column reports, from left to right, the total number of tracked cells, the subset identified as backward shifting, those identified as forward shifting, and the remaining cells not classified as forward or backward shifting. b, Same layout as in a, but showing the proportion of cells rather than absolute counts. The numbers in the first column are normalized by the total number of tracked cells for each mouse, and subsequent columns are normalized within each cell type (for example, 47 backward-shifting reward cells out of 228 total tracked reward cells). c. Percentage of backward- and forward-shifting cells for each cell type. Reward and reward-approach cells show a higher tendency for backward shifting, whereas screen cells more frequently show forward shifting. Non-classified cells exhibit no strong bias, with roughly equal proportions of forward and backward shifting. d, Correlation of peak activity timing and session number across cell types. e, Temporal shifting score across cell types. For d,e: 228 reward cells, 53 were reward-approach cells, 225 screen cells and 1,308 non-classified cells. Bar graphs and error bars in d,e show mean ± s.e.m.

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