Extended Data Fig. 11: Distribution of amplitude-changing cells across mice.

a, The first row shows the total number of tracked cells for each functional cell type, while the second row breaks these numbers down by mouse (mouse 2 had poor cell tracking and was excluded from this analysis). Each column reports, from left to right, the total number of tracked cells per cell type, the number of cells identified as declining cells, the number of cells identified as inclining cells, and those identified as forward shifting, and the number of tracked cells not classified as declining or inclining cells. b, Same layout as in a, but showing the proportion of cells rather than absolute counts. The numbers in the first column are normalized by the total number of tracked cells for each mouse, and subsequent columns are normalized within each cell type (for example, 49 declining reward cells out of 228 total tracked reward cells). c. Percentage of declining and increasing cells for each cell type. All three cell types exhibit a higher tendency to decline. Non-classified cells exhibit no strong bias, with roughly equal proportions of declining and inclining. d, Correlation of response amplitude and session number across cell types. e, Amplitude change score across cell types. For d,e: 228 reward cells, 53 were reward-approach cells, 225 screen cells and 1,308 non-classified cells. Bar graphs and error bars in d,e show mean ± s.e.m.