Extended Data Fig. 5: T cell clones shared between the ME and dura mater.
From: Intestinal macrophages modulate synucleinopathy along the gut–brain axis
a, Boxplot quantifying the effective number of species (reciprocal of the unbiased estimator of Simpson’s diversity) in the dura mater and ME of NHC-αS and PD-αS injected groups for the alpha (A) and beta (B) T cell receptor chains. Data analysed using a Bonferroni-adjusted unpaired t test with Welch’s correction. Data are shown as boxplots: the median is the central line; hinges indicate the first and third quartiles; whiskers extend to the most extreme values within 1.5×IQR; and points beyond the whiskers are plotted as individual outliers. n = 4 mice per condition over 1 experiment. b,c, Alluvial plots of the top 10 most frequent T cell clones present in both the ME and in the dura mater of the alpha chain (a) and beta chain (b) of the PD-αS vs NHC-αS injected groups.
