Extended Data Fig. 3: Genetic affinity of UV ancient individuals to other Ancient American Groups.
From: Local agricultural transition, crisis and migration in the Southern Andes

a-b. Heatmaps summarizing Z-scores derived from f4(Mbuti, Uspallata; Ancient American Group 1, Ancient American Group 2), where Ancient American Groups 1 and 2 are represented by point type and colours on the x and y axes, respectively. Ancient groups whose individuals were sequenced through shotgun are marked with black dots. Ancient American groups are ordered by major geographical ranges and periods. Z-scores greater and lower than 0 are coloured in shades of yellow to red and light blue to dark blue, respectively. Results are shown when only including American groups from Early (EH) and Mid-Holocene (MH) in the comparisons (b) or also including Late Holocene (LH) groups (a). f4 were computed considering all autosomal positions on the 1240 K (see Fig. S24 for results on other SNP panels). c-d. Z-scores derived from f4(Mbuti, Ancient Central or North American Group; UV, Ancient South American Group) are shown by grouping the Ancient Central and North American groups along the x-axis by geographical range and period. Points are represented according to the Ancient South American Group. In one column (one violin plot), South American Groups appear N times when the grouping on the x-axis includes N Central or North American groups. Dashed lines for |Z| = 3 are used as thresholds for significance. Results are shown when only including South American groups from Early (EH) and Mid- Holocene (MH) in the comparisons (d) or also including Late Holocene groups (LH) (c). f4 were computed considering all autosomal positions on the 1240 K (see Fig. S25 for results on other SNP panels).