Extended Data Fig. 8: Sex differences in PFA tumour fractions on the basis of hierarchical classification, deconvolution and integration with the developing glial lineage.
From: Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma
a, Integrated cell-type proportion in PFA tumour cells per sample by sex. b, Fraction of CHETAH matched cells across glial cell types and intermediate nodes for PFA tumour cells by sample per sex. c, BayesPrism deconvoluted glial lineage cell-type proportion in PFA tumour fraction pseudobulk per sample by sex. a–c, Female (n = 8) and male (n = 18). In box plots, the centre line denotes the median, box hinges indicate the 25th and 75th percentiles, and whiskers mark 1.5× the IQR. P values were calculated using a two-sided Student’s t-test. *P < 0.05, **P < 0.01; NS, not significant. Exact P values are provided in the Source Data.
