Extended Data Fig. 1: Cryo-EM structure determination of TNFR1-DD, TRADD-DD and RIPK1-DD helical filaments.
From: Electric dipole moment drives the dynamics of the TNFR1 complex I signalosome
a, Fluorescence images of HeLa cells expressing mEGFP-tagged TNFR1-DD, TRADD-DD or RIPK1-DD. b, Flow chart for the cryo-EM structure determination of TNFR1-DD, TRADD-DD, RIPK1-DD filaments and the local resolution filtered map calculated with FSC 0.143 criterion. c, The FSC curve calculated between two half maps of the refined final density volume. d, Electrostatic potential surface representation of the cryo-EM structures of TNFR1-DD, TRADD-DD and RIPK1-DD filaments. Results are representative of three independent experiments for (a).
