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Anatomy of the 23andMe fall and implications for consumer genomics

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23andMe’s bankruptcy serves as a moment of reflection for the direct-to-consumer (DTC) genomics industry. We analyzed 23andMe financial data and business practices to reveal the factors behind the fall of the company, once valued at US $6 billion and now being considered for acquisition by Regeneron for merely $250 million. Key challenges faced by 23andMe in monetizing its genomic data reveal that this information, at least in a typical DTC setting, is simply not worth that much.

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Fig. 1: Key performance indicators of 23andMe since going public in 2021.

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  • 03 June 2025

    In the version of this article initially published, the correct affiliation for Dina Zielinski (Geneticancer, Paris, France) was not listed, while in Table 1, the status for Knome (Acquired by Tute Genomics) was incorrect. The affiliation and table are now corrected in all versions of the article.

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Correspondence to Yaniv Erlich or Dina Zielinski.

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Competing interests

Y.E. is an employee and shareholder of Eleven Therapeutics, an RNA Therapeutic start-up. D.Z. is an employee and shareholder of WhiteLab Genomics, a gene and cell therapy company.

Supplementary information

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Supplemental Figure 1-3, Supplemental Note 1-3

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Quarterly analysis of public financial information

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Erlich, Y., Zielinski, D. Anatomy of the 23andMe fall and implications for consumer genomics. Nat Biotechnol 43, 854–856 (2025). https://doi.org/10.1038/s41587-025-02683-z

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