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Non-profits wade in where for-profit life science investment fears to tread

For decades, and in the exceptional instance of the Institut Pasteur for over a century, non-profit organizations have augmented R&D to advance scientific understanding and develop affordable and accessible pipelines of vaccines, medicines and diagnostics. Small and medium enterprises and former biopharmaceutical industry executives make a sizeable contribution to global health goals by pursuing opportunities in this corner of the global biopharmaceutical ecosystem.

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Fig. 1: Number of candidates or products by organization type.

References

  1. Willis, J. R. et al. Science https://doi.org/10.1126/science.adr8382 (2025).

    Article  PubMed  Google Scholar 

  2. Impact Global Health. The 2025 neglected disease R&D pipeline review: time to close the gaps. https://www.impactglobalhealth.org/insights/report-library/the-2025-neglected-disease-rd-pipeline-review (2025).

  3. Impact Global Health. 100 Days Mission: 4th implementation report and scorecard. https://www.impactglobalhealth.org/insights/report-library/ipps-report-2025 (2025).

  4. Levinson, K. J. et al. Vaccines https://doi.org/10.1016/j.vaccine.2016.10.023 (2016).

    Article  Google Scholar 

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Nasto, B. Non-profits wade in where for-profit life science investment fears to tread. Nat Biotechnol 43, 1221–1226 (2025). https://doi.org/10.1038/s41587-025-02752-3

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