Extended Data Fig. 5: PTBP1-Associated RNAs.
From: Genome-wide mapping of RNA-protein associations through sequencing
(a) Distribution of PTBP1 target RNAs identified by PRIM-seq, highlighting the subset that overlaps with entries in the RNAInter database (pink) versus novel targets (green). (b) Motif frequency (y-axis) and statistical enrichment (x-axis, –log[p-value]) for each of the two de novo motifs uncovered by PRIM-seq. (c, d) An example depicting the ‘CUCUCUCUGG’ motif (red block) within a PRIM-seq peak (pink track). (e) Alignment of the top de novo motif (top) with the known PTBP1 motif (bottom), underscoring their strong similarity.
