Extended Data Fig. 2: H9-scNSC Grafts in Monkeys that Underwent Hemi-contusions.

(A) S121 labeling for human cells demonstrates grafts in lesion sites of each contused monkey. There is excellent graft fill of the lesion site in 6 monkeys (#’s 9, 11-15). One monkey, #10, has surviving graft in only the rostral portion of the lesion site: this monkey therefore had very few detectable caudal axons (Fig. 6g). Monkey #10 also exhibited good functional improvement, but had the smallest contusion lesion volume among all animals (less than half the size of the mean lesion volume) and considerable right-sided tissue sparing. Thus, recovery in this subject was likely attributable to lesion incompleteness. (B) S121 labeling in contused monkeys lacking surviving grafts. Scale Bars: 1 mm.