Extended Data Fig. 3: NAPA modification saturation.
From: Mapping single-cell diploid chromatin fiber architectures using DAF-seq
Boxplots showing modification percentages of each applicable position within the NAPA promoter for targeted DAF-seq (red, n = 188 positions) or Fiber-seq libraries (purple, n = 125 positions each). NAPA promoter modification rates were significantly higher in GM12878 cells in targeted DAF-seq than Fiber-seq (one-sided t-test, P = 1.7 × 10−11, t = 6.97, df = 228, 95% CI = 0.15 - ∞). Boxes represent the median and interquartile range and whiskers extend to the farthest samples within 1.5× the interquartile range of the median.
