Extended Data Fig. 6: Characterization of truncated vector genomes by single-molecule nanopore sequencing.
From: An engineered UGA suppressor tRNA gene for disease-agnostic AAV delivery
(a) Coverage plot of the sequencing reads mapped to the reference vector genome (VG). The vector genome elements are illustrated to scale. (b) Virtual gel image generated with the sequencing reads mapped to the reference VG. For truncated vector genomes, the lost DNA elements due to recombination are illustrated with dashed borders. A single AAV preparation lot was used for each vector.
