Extended Data Fig. 1: Schematic representation and AutoCAD designs of the polydimethylsiloxane (PDMS) chip for MAGIC-seq.

a. Design of triple-grid chips X and Y; each chip possesses 70 channels with a channel width of 50 μm. b. Design of nine-grid chips X and Y; each chip possesses 70 channels with a channel width of 50 μm. c. Design of splicing-grid chips X, Y and Z; chips X and Y possess 70 channels with a channel width of 50 μm. d. Design of splicing-grid chips X, Y and Z; chips X and Y possess 70 channels with a channel width of 15 μm.