Extended Data Fig. 3: Clustering analysis and comparison between MAGIC-seq and 10x Visium. | Nature Genetics

Extended Data Fig. 3: Clustering analysis and comparison between MAGIC-seq and 10x Visium.

From: Custom microfluidic chip design enables cost-effective three-dimensional spatiotemporal transcriptomics with a wide field of view

Extended Data Fig. 3

a. UMAP plots of MAGIC-seq and 10x Visium samples based on gene expression. The colored dots represented spots from different samples (top) and clusters (bottom). b. Spatial distribution of clusters across different mouse brain samples from MAGIC-seq and 10x Visium. Samples starting with ‘grid’ were processed by MAGIC-seq at 50 μm resolution and samples starting with ‘Visium’ were processed by 10x Visium for comparison. c. Correlation analysis of gene expression among different samples. R, Spearman correlation coefficient. d. Mean expression of top 5 marker genes for each cluster across different samples. Each row represents a cluster from a sample, and each column represents a gene.

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