People with disabilities are under-represented in general (non-disability-specific) precision medicine research (PMR), limiting access to its benefits. We examine key reasons for this, focusing on the role of (dis)trust, and identify areas for further inquiry to guide researchers and enhance PMR’s trustworthiness for people with disabilities.
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Acknowledgements
This work was supported by NHGRI/NIH’s Office of the Director grant R01HG010868.
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M.S. is a member of the Institutional Review Board of the All of Us Research Program. The other authors declare no competing interests.
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Aguirre, A., Lee, S.SJ., Callier, S. et al. Towards trustworthiness of precision medicine research for people with disabilities. Nat Genet 57, 1321–1324 (2025). https://doi.org/10.1038/s41588-025-02195-1
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DOI: https://doi.org/10.1038/s41588-025-02195-1
