Extended Data Fig. 3: Cell-type distribution by stricture status in scRNA-seq data. | Nature Genetics

Extended Data Fig. 3: Cell-type distribution by stricture status in scRNA-seq data.

From: Single-cell and spatial transcriptomics of stricturing Crohn’s disease highlights a fibrosis-associated network

Extended Data Fig. 3: Cell-type distribution by stricture status in scRNA-seq data.The alternative text for this image may have been generated using AI.

a, Barplots show significant differences in cell-type frequency for non-IBD (green) and non-stricture (blue) samples relative to stricture (red) samples in immune, stromal epithelial and epithelial fraction immune compartments. *padj. < 0.05, **padj. < 0.01 (Wald test from Dirichlet regression with FDR correction; Methods). Blue asterisks indicate overrepresentation in non-stricture or non-IBD vs. stricture samples, while red asterisks indicate underrepresentation. Error bars are s.e.m. The total number of cells contributing to each bar is also shown. b, Similar to a, only using paired stricture and non-stricture samples (Methods).

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