Extended Data Fig. 7: asRS and asRT events are both important contributors to gene expression. | Nature Genetics

Extended Data Fig. 7: asRS and asRT events are both important contributors to gene expression.

From: Genetic variants affecting RNA stability influence complex traits and disease risk

Extended Data Fig. 7: asRS and asRT events are both important contributors to gene expression.The alt text for this image may have been generated using AI.

a, Proportion of asRS and asRT variants in each cell line (n = 11) that overlapped expression quantitative trait loci (eQTLs) (p = 3.71e-20). P value was calculated via a two-sided Wilcoxon’s signed rank-test. In boxplots, minima/maxima represent least/greatest proportion values, bounds show 25th and 75th percentiles, and whiskers indicate values within 1.5 * the interquartile range. b, Enrichment (that is Fisher’s exact test odds ratio) of asRS genes that overlap eGenes (compared to asRT genes).*p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001. None of the comparisons in which the asRT overlap proportion was higher than the asRS overlap proportion were significant.

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