Extended Data Fig. 2: Independent replication of genetic signals.
From: A genetic map of human metabolism across the allele frequency spectrum
a, Replication of estimated genetic effects on circulating metabolites in Karjalainen et al.3. Bar plots represent the correlation of effect sizes (top), correlation between the P-value (middle), and the fraction of our sentinel variants that reached genome-wide significance in the replication study (bottom). b, Identical to a but using data from Tambets et al.9. For both comparisons, we only considered directly measured traits.
