Extended Data Fig. 1: scRNA-seq data quality control and zonation annotation for Visium ST data.
From: Spatially resolved multi-omics of human metabolic dysfunction-associated steatotic liver disease
a, Violin plots summarizing the number of UMIs detected per cell (total_counts), detected genes per cell (n_genes_by_counts) and the proportion of reads incident to mitochondrial genes (pct_counts_mt) per sample before (top) and after (bottom) filtering low-quality cells. b, Dot plots summarizing the known markers used to identify cell types. Each column corresponds to a specific cell subcluster and rows correspond to a list of key marker genes (expression normalized per gene), brackets on the right side of each plot detail the cell type or subcluster that these genes mark. c, Spatial distribution of four lobule zones (portal, peri-portal, mid and central) across all 35 Visium sections.
