Extended Data Fig. 6: Age at onset and survival analyses.
From: Large-scale exome analyses reveal new rare variant contributions in amyotrophic lateral sclerosis
a, b, Age at onset analyses (left) and survival analyses (right) for significant variants (a) and significant genes among URV burden analyses (b). Estimates in years (center) and 95% confidence intervals (error bars) are shown for age at onset analyses in 10,557 participants (linear model), and log-transformed hazard ratios (center) and 95% confidence intervals (error bars) are shown for survival analyses in 7,194 participants (Cox proportional hazards model). Closed circles indicate variants or genes that reached significance corrected for the number of variants or genes tested.
