Extended Data Table 3 Cumulative percentage of patients carrying ALS-associated variants

From: Large-scale exome analyses reveal new rare variant contributions in amyotrophic lateral sclerosis

  1. The table shows the percentage of ALS patients carrying at least one (≥1), exactly one (1), two (2), or three (3) qualifying variants identified in this study. Each row represents the cumulative proportion of patients relative to the row above it, starting with single variants (sv) and adding qualifying variants (URV) in genes identified in the burden analyses. *Data on the C9orf72 (C9) repeat expansion was available for 66% of patients. When only single variants + C9 status are considered, the percentages are 22.9% (≥1), 20.5% (1), 2.36% (2) and 0.09% (3), respectively. sv, single variants; URV, ultra-rare variants.
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