Extended Data Fig. 2: SCZ GWAS27 loci with a PP4 > 0.8 and significant MR association in SingleBrain and MiGA. | Nature Genetics

Extended Data Fig. 2: SCZ GWAS27 loci with a PP4 > 0.8 and significant MR association in SingleBrain and MiGA.

From: A meta-analysis of single-nucleus expression quantitative trait loci linking genetic risk to brain disorders

Extended Data Fig. 2: SCZ GWAS27 loci with a PP4 > 0.8 and significant MR association in SingleBrain and MiGA.

The circle represents expression quantitative trait loci (eQTLs) with a PP4 > 0.8. Triangles denote significant genes in the Mendelian randomization (MR) results, with the orientation of the triangle corresponding to the direction of the effect. COLOC, colocalization; MR, Mendelian randomization; MiGA, Microglia Genomic Atlas; MG, microglia; Ext, excitatory neuron; IN, inhibitory neuron; Ast, astrocyte; OD, oligodendrocyte; OPC, oligodendrocyte progenitor cell; End, endothelial cell.

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