Extended Data Fig. 6: Cryo-EM reconstruction of SARS-CoV-2 Spike trimer.
From: Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2
The SARS-CoV-2 Spike trimer + VH3 B01 cryo-EM reconstruction from non-uniform refinement in cryoSPARC at two different thresholds colored by resolution in the range from 3 Å to 10 Å. At high threshold the core S2 clearly displays high resolution features but the periphery of the molecule is closer to 6-7 Å.
