Extended Data Fig. 7: pH dependent binding of lead multivalent and bi-paratopic VH.
From: Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2
BLI assay of lead constructs at 25 nM to Secto and RBD at pH 7.4 or pH 4.5. Binding of VH leads is only observed with Secto at pH 7.4 and RBD at pH 4.5.
